Indications

Acute diarrhoea, Chronic diarrhoea

Contraindication

Conditions when inhibition of peristalsis is to be avoided; antibiotic-associated colitis, acute ulcerative colitis, bacterial enterocolitis, acute inflammatory bowel disease, abdominal distention.

Special Precautions

Not intended for use as a primary treatment in acute dysentery. Hepatic impairment. Childn. Pregnancy and lactation. Patient Counselling This drug may cause drowsiness or dizziness, if affected it may impair ability to drive or operate machinery. Monitoring Parameters Monitor for signs of CNS toxicity (in patients w/ hepatic impairment).

Side Effects

Abdominal pain or bloating, nausea and vomiting, constipation, dry mouth, drowsiness, dizziness, fatigue, epigastric pain, hypersensitivity reactions (e.g. rash).

Drug Interactions

Increased plasma levels w/ P-glycoprotein inhibitors (e.g. quinidine, ritonavir). May decrease exposure to saquinavir.

Route of Administration

Oral

Dosage

As directed by the physician