Indications

Treatment and prevention of Asthma

Contraindication

Oral inhalation: Primary treatment of acute asthmatic attacks or status asthmaticus when intensive measures are required. Rectal: Hepatic cirrhosis w/ signs of portal HTN.

Special Precautions

Patient w/ TB, fungal or viral infections in the airways, CV disease, osteoporosis, peptic ulcer, cataracts, thyroid disease, seizure disorder; existing or family history of severe affective disorder, DM and glaucoma. Not intended for relief of acute bronchospasm. Avoid abrupt withdrawal when switching from systemic to oral or orally inhaled corticosteroid. Hepatic and renal impairment. Childn. Pregnancy and lactation. Monitoring Parameters Monitor BP, serum glucose, growth in paed patients; signs and symptoms of hypercorticism or adrenal suppression.

Side Effects

Cushing's syndrome, adrenal suppression, growth retardation, decreased bone density, cataract, glaucoma, psychiatric/behavioural effects.

Drug Interactions

Increased systemic exposure w/ potent CYP3A4 inhibitors (e.g. ketoconazole). Decreased systemic exposure w/ CYP3A4 inducers (e.g. carbamazepine).

Route of Administration

Oral

Dosage

As directed by the physician