Indications

Type 2 DM.

Special Instructions

May be taken with or without food.

Special Precautions

Patient w/ cardiac failure (NYHA functional class IV), type 1 DM; history of acute pancreatitis. Not intended for the treatment of diabetic ketoacidosis. Hepatic impairment, including patients w/ pre-treatment ALT or AST >3 times the upper limit of normal (ULN). Moderate or severe renal impairment, ESRD. Monitoring Parameters Monitor liver function.

Side Effects

Nausea, peripheral oedema, headache, tremor, asthenia, dizziness, constipation, hypoglycaemia, arthralgia, hepatic dysfunction, nasopharyngitis, upper resp tract infection, pancreatitis, exfoliative and bullous skin reactions.

Drug Interactions

Decreased hypoglycaemic effect w/ thiazides, corticosteroids, thyroid products and sympathomimetics.

Route of Administration

Oral

Dosage

As directed by the physician